An electron microscope allows the direct imaging of objects at high resolution using an electron beam. As in light microscopy, the resolution is determined by the wavelength. Compared to visible light, accelerated electrons have a much smaller wavelength, so that the theoretical resolution limit is smaller than 0.1 nm and is only limited by the biological properties of the objects. Although the sample preparation and evaluation in electron microscopy (EM) is more time-consuming in comparison to other microscopic methods, the unchallenged advantage of the best resolution in combination with the "open view" of the full ultrastructural context makes EM so attractive for research.

In addition to classical EM techniques, modern EM encompasses a number of technological advancements. In particular, 3D techniques and correlative light-electron microscopical techniques have broadened our approaches to better understand cell structures down to the molecular level.

The CFEM offers both the infrastructure and the expertise to perform EM projects. We advise users on project planning and implementation (sample fixation and preparation) as well as evaluation of collected data. The services also include individual user trainings so that an independent working on the microscopes is possible. Upon request, we also process projects as full-service, whereby the sample fixations, preparations and the processing at the electron microscopes are being performed by members of the CFEM.